Ear involvement in acute promyelocytic leukemia

Ear involvement in acute promyelocytic leukemia.

448 A 44 ‐year ‐old woman with acute promyelo‐ cytic leukemia (APL) presented to our depart‐ ment in an overall bad condition with hearing loss, severe headache, and severe weakness. Two years earlier, she had been diagnosed with APL with 46,XX, t(15;17)(q24;q21), del (16)(q11;q22), add(7)(p21), add (X)(p22), and detectable PML/RARα and FLT3 ‐ITD mutations, and had been successfully treated wit...

Acute myeloid leukemia and acute promyelocytic leukemia.

The therapeutic approach to the patient with acute myeloid leukemia (AML) currently evolves toward new frontiers. This is particularly apparent from the entree of high-throughput diagnostic technologies and the identification of prognostic and therapeutic targets, the introduction of therapies in genetically defined subgroups of AML, as well as the influx of investigational approaches and novel...

Acute promyelocytic leukemia?

Briefly, the important clinical findings were as follows: A 10 year old white girl, acutely ill, febrile and showing disseminated skin purpura. There was no visceromegaly. The disease had apparently started 3 weeks before, with epistaxis and other purpuric manifestations. Laboratory findings showed severe anemia and thrombocytopenia with a leukocyte count of 3500 per cu. mm. The differential co...

[Acute promyelocytic leukemia].

Acute promyelocytic leukemia.